Job Description

Job Title: Clinical Research Nurse II (Oncology)

Location: Onsite – San Diego, CA

Schedule: Full-Time, Monday - Friday (flexible hours; no overtime expected)

Compensation: $150,000 – $250,000 annually

Position Overview:

An oncology research site is seeking an experienced Clinical Research Nurse II to support and help lead oncology clinical trials. This role will function as both a research nurse and team lead, acting as a key clinical and operational partner across research trials.

The Clinical Research Nurse II will serve as a central point of coordination between physicians, clinical research staff, and patients, while also helping bring structure, accountability, and strong clinical judgment to a growing program. This is an excellent opportunity for a research nurse who thrives in a collaborative environment and is ready to take on increased ownership and informal leadership responsibilities.

Key Responsibilities:

• Serve as the primary clinical resource for oncology clinical trials
• Act as a lead nurse and day-to-day resource for research staff, helping guide workflow, answer questions, and support trial execution
• Collaborate closely with a team of physicians, including two primary physician partners, as well as Clinical Research Coordinators (CRCs)
• Coordinate and manage patient care within clinical trials, including screening, enrollment, treatment administration support, and follow-up
• Ensure adherence to study protocols, regulatory requirements, and institutional standards, helping reinforce compliance and best practices
• Partner with investigators and study teams to resolve clinical and operational challenges in real time
• Support communication with sponsors, monitors, and internal stakeholders as needed
• Contribute to process improvements and help establish more structured, compliant workflows across the team
• Function in a Research Nurse Case Manager capacity, maintaining continuity of care for study participants

Qualifications:

• Active Registered Nurse (RN) license in California
• Bachelor of Science in Nursing (BSN) required
• Minimum of 2+ year of clinical research nursing experience
• Oncology nursing experience required; pancreatic cancer experience strongly preferred
• ONS (Oncology Nursing Society) certification required or willingness to obtain within a defined timeframe
• Experience supporting clinical trials, including patient management and protocol adherence
• Comfortable working closely with physicians in a collaborative, fast-paced environment
• Academic medical center experience is a plus, but not required

Key Competencies:

• Strong clinical judgment and decision-making skills, with the confidence to operate independently and advocate for best practices
• Ability to navigate complex situations and maintain accountability across teams
• Excellent interpersonal and communication skills, particularly in working with physicians and cross-functional teams
• Detail-oriented with a strong commitment to patient safety, protocol compliance, and data integrity
• Adaptable and solutions-oriented, with the ability to bring structure to evolving processes
• Team-oriented mindset with the ability to influence without direct authority

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